Psilocybin research evidence map
Does one dose of psilocybin rewire the brain?
Explore the papers behind each claim and the reasons those claims are connected. These are source links and editorial assessments; proposed interpretations remain questions.
24 source papers · 23 claims · 13 relationships
Synthesis updated
Showing 24 of 24 papers and 23 of 23 claims
Jump to selected detailsSelected Claim 1. In healthy volunteers, a single 25 mg dose left enduring functional brain changes “largely absent” one month later, though some diffusion-imaging and network-modularity signals persisted; what lasted was mainly psychological: well-being and insight.
Position and line length are for readability. They do not measure similarity, effect size or certainty. Paper-to-paper citations are not shown.
Browse as a list · 23 claims
Lyons 2026
Read the claim and sourcesDaws 2022
Read the claim and sourcesDaws 2022
Read the claim and sourcesJiang 2026
Read the claim and sourcesNardou 2023
Read the claim and sourcesNardou 2023, Lyons 2026, Shao 2021
Read the claim and sourcesSiegel 2024
Read the claim and sourcesGoodwin 2022
Read the claim and sourcesCarhart-Harris 2021
Read the claim and sourcesShao 2021
Read the claim and sourcesLyons 2026, Daws 2022, Carhart-Harris 2021, Pasquini 2026, Harding 2025, Erritzoe 2024
Read the claim and sourcesNovelli 2025
Read the claim and sourcesJohansen 2026
Read the claim and sourcesPasquini 2026
Read the claim and sourcesBhagavan 2026
Read the claim and sourcesMadsen 2024, Brendstrup-Brix 2026
Read the claim and sourcesHarding 2025
Read the claim and sourcesFarré-Colomés 2026, Sabbah 2026
Read the claim and sourcesKramer 2026
Read the claim and sourcesGudmundsen 2026
Read the claim and sourcesKeenan 2026
Read the claim and sourcesSahoo 2026, García-Cabrerizo 2025
Read the claim and sourcesRaison 2023, Erritzoe 2024
Read the claim and sources
What is included, and when it changes
The map follows the published synthesis. A new discovery enters the published map only through a versioned update. Line length is a layout choice, not an evidence score. Semantic similarity and paper-to-paper citation networks are not included in this version.
Latest saved discovery scan: . It contains 1593 discovered candidates. Screening status is not recorded in this snapshot. Discovered candidates are not automatically included as evidence.
Editorial assessment is not independent scientific validation. Review status and limitations remain attached to the full claims.
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